Clinical manifestations disease occurs in either of two general forms depending upon the virus one is typified by fever malaise headache and or symptoms of . 22 togaviridae and flaviviridae the alphaviruses and flaviviruses 415 ing ill wn je rsse and sle viruses were all isolated prior to 1940 karabatsos 1985. The publication of this volume of the viruses entitled the togaviridae and flaviviridae comes at an appropriate time the structure and rep lication strategies of
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